Congratulations to lab member Ryan Passino for his paper in Cell Reports showing how different myeloid cell types impact optic nerve regeneration!
https://pubmed.ncbi.nlm.nih.gov/38492223/
Congratulations to lab member Ligia Schmitd for her talk at the Myelin Gordon Research Conference!
Congratulations to lab member Ayo Ward on receiving a Merkin PNNR Fellowship Award for his investigation of injured human peripheral nervous tissue.
Congratulations to lab member Ryan Passino on successfully defending his dissertation entitled “Immune-Mediated Retinal Ganglion Cell Axon Regeneration: The Role of Neutrophil-Induced Vascular Damage and Microglial Protection.”
Congratulations to lab member Hannah Hafner for receiving a top 5% score on the F31 Ruth Kirschstein Fellowship!
Congratulations to lab member Mitre Athaiya for winning Best Poster Award at the Gordon Research Conference on Central Nervous System Injury and Repair!
New Publication!
Like all receptor tyrosine kinases (RTKs), ErbB4 signals through a canonical signaling involving phosphorylation cascades. However, ErbB4 can also signal through a non‑canonical mechanism whereby the intracellular domain is released into the cytoplasm by regulated intramembrane proteolysis (RIP) and translocates to the nucleus where it regulates transcription. These different signaling mechanisms depend on the generation of alternative spliced isoforms, a RIP cleavable ErbB4‑ JMa and…
New Publication from the Giger lab!
Hedgehog signaling controls tissue patterning during embryonic and postnatal development and continues to play important roles throughout life. Characterizing the full complement of Hedgehog pathway components is essential to understanding its wide-ranging functions. Previous work has identified neuropilins, established semaphorin receptors, as positive regulators of Hedgehog signaling. Neuropilins require plexin co-receptors to mediate semaphorin signaling, but the role of plexins in Hedgehog signaling has not…
Congratulations to Dr. Ligia Buloto-Schmitd on her TEAM T32 Training Grant Re-appointment!
The Giger laboratory is extremely proud of Dr. Ligia Buloto-Schmitd on her re-appointment with the NIH TEAM T32 Training Grant. This opportunity will support Ligia in a variety of ways to continue the important research that she is currently conducting in the laboratory. Job well-done, Dr. Buloto-Schmitd!