New Publication! Click here for more info.

Abstract During mammalian neocortex development, nascent pyramidal neurons migrate along radial glial cells and overtake earlier-born neurons to terminate at the front of the developing cortical plate (CP), leading to the outward expansion of the CP border. While much has been learned about the cellular and molecular mechanisms that underlie the migration of pyramidal neurons, how migrating neurons bypass the preceding neurons at the end…

New Publication!

Neuronal injury can cause mitochondrial damage, leading to reduced energy production, decreased Ca2+ storage capacity, and increased reactive oxygen species. A new study reveals a mechanism to trigger the axonal transport of previously anchored mitochondria and promote neuroprotection and axon regeneration by replacing damaged with functional mitochondria. Check out the full article to learn more by clicking the link below! LINK: Neurobiology: Resetting the axon’s batteries…

Dissertation Defense – Lucas Huffman

Please join us for the defense of Lucas Huffman “More than Clearing the Clutter: The Imperative Role of Efferocytosis in Repair and Reprogramming in the Damaged Nervous System” Date: Friday, June 25, 2021 Time: 10AM EST Location: Zoom “More than Clearing the Clutter: The Imperative Role of Efferocytosis in Repair and Immune Reprogramming in the Damaged Nervous System” Dr. Roman Giger, Chair Evolutionarily, the nervous…

New publication in ELife “Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement.”

The Giger lab is proud to announce the publication of our latest paper through ELife “Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement.” Thank you to everyone involved! https://elifesciences.org/articles/60223