Publications

Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition.

Kalinski AL, Kar AN, Craver J, Tosolini AP, Sleigh JN, Lee SJ, Hawthorne A, Brito-Vargas P, Miller-Randolph S, Passino R, Shi L, Wong VSC, Picci C, Smith DS, Willis DE, Havton LA, Schiavo G, Giger RJ, Langley B, Twiss JL.

J Cell Biol. 2019 Jun 3;218(6):1871-1890. doi: 10.1083/jcb.201702187. Epub 2019 May 8.PMID: 31068376

Protective role of the lipid phosphatase Fig4 in the adult nervous system.

Mironova YA, Lin JP, Kalinski AL, Huffman LD, Lenk GM, Havton LA, Meisler MH, Giger RJ.

Hum Mol Genet. 2018 Jul 15;27(14):2443-2453. doi: 10.1093/hmg/ddy145.PMID: 29688489

PlexinA2 Forward Signaling through Rap1 GTPases Regulates Dentate Gyrus Development and Schizophrenia-like Behaviors.

Zhao XF, Kohen R, Parent R, Duan Y, Fisher GL, Korn MJ, Ji L, Wan G, Jin J, Püschel AW, Dolan DF, Parent JM, Corfas G, Murphy GG, Giger RJ.

Cell Rep. 2018 Jan 9;22(2):456-470. doi: 10.1016/j.celrep.2017.12.044.PMID: 29320740 

LRP1 regulates peroxisome biogenesis and cholesterol homeostasis in oligodendrocytes and is required for proper CNS myelin development and repair.

Lin JP, Mironova YA, Shrager P, Giger RJ.

Elife. 2017 Dec 18;6. pii: e30498. doi: 10.7554/eLife.30498.PMID: 29251594 

Neuropilin-1 promotes Hedgehog signaling through a novel cytoplasmic motif.

Pinskey JM, Franks NE, McMellen AN, Giger RJ, Allen BL.

J Biol Chem. 2017 Sep 15;292(37):15192-15204. doi: 10.1074/jbc.M117.783845. Epub 2017 Jun 30.PMID: 28667171 

Nogo receptor blockade overcomes remyelination failure after white matter stroke and stimulates functional recovery in aged mice.

Sozmen EG, Rosenzweig S, Llorente IL, DiTullio DJ, Machnicki M, Vinters HV, Havton LA, Giger RJ, Hinman JD, Carmichael ST.

Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):E8453-E8462. doi: 10.1073/pnas.1615322113. Epub 2016 Dec 12.PMID: 27956620 

Reassembly of Excitable Domains after CNS Axon Regeneration.

Marin MA, de Lima S, Gilbert HY, Giger RJ, Benowitz L, Rasband MN.

J Neurosci. 2016 Aug 31;36(35):9148-60. doi: 10.1523/JNEUROSCI.1747-16.2016.PMID: 27581456 

An evolutionarily conserved mechanism for cAMP elicited axonal regeneration involves direct activation of the dual leucine zipper kinase DLK.

Hao Y, Frey E, Yoon C, Wong H, Nestorovski D, Holzman LB, Giger RJ, DiAntonio A, Collins C.

Elife. 2016 Jun 7;5. pii: e14048. doi: 10.7554/eLife.14048.PMID: 27268300 

Semaphorin 3A is a retrograde cell death signal in developing sympathetic neurons.

Wehner AB, Abdesselem H, Dickendesher TL, Imai F, Yoshida Y, Giger RJ, Pierchala BA.

Development. 2016 May 1;143(9):1560-70. doi: 10.1242/dev.134627.PMID: 27143756 

PI(3,5)P2 biosynthesis regulates oligodendrocyte differentiation by intrinsic and extrinsic mechanisms.

Mironova YA, Lenk GM, Lin JP, Lee SJ, Twiss JL, Vaccari I, Bolino A, Havton LA, Min SH, Abrams CS, Shrager P, Meisler MH, Giger RJ.

Elife. 2016 Mar 23;5. pii: e13023. doi: 10.7554/eLife.13023.PMID: 27008179 

Stable biomarker for plastic microglia.

Segal BM, Giger RJ.

Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3130-2. doi: 10.1073/pnas.1601669113. Epub 2016 Mar 10. No abstract available.PMID: 26966229 

Inside Out: Core Network of Transcription Factors Drives Axon Regeneration.

Yoon C, Giger RJ.

Neuron. 2016 Mar 2;89(5):881-4. doi: 10.1016/j.neuron.2016.02.022.PMID: 26938435 

Rescue of neurodegeneration in the Fig4 null mouse by a catalytically inactive FIG4 transgene.

Lenk GM, Frei CM, Miller AC, Wallen RC, Mironova YA, Giger RJ, Meisler MH.

Hum Mol Genet. 2016 Jan 15;25(2):340-7. doi: 10.1093/hmg/ddv480. Epub 2015 Nov 24.PMID: 26604144 

Th Cell Diversity in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis.

Carbajal KS, Mironova Y, Ulrich-Lewis JT, Kulkarni D, Grifka-Walk HM, Huber AK, Shrager P, Giger RJ, Segal BM.

J Immunol. 2015 Sep 15;195(6):2552-9. doi: 10.4049/jimmunol.1501097. Epub 2015 Aug 3.PMID: 26238492 

Insights into the physiological role of CNS regeneration inhibitors.

Baldwin KT, Giger RJ.

Front Mol Neurosci. 2015 Jun 11;8:23. doi: 10.3389/fnmol.2015.00023. eCollection 2015. Review.PMID: 26113809 

Neuroinflammation triggered by β-glucan/dectin-1 signaling enables CNS axon regeneration.

Baldwin KT, Carbajal KS, Segal BM, Giger RJ.

Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2581-6. doi: 10.1073/pnas.1423221112. Epub 2015 Feb 9.PMID: 25675510 

Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells.

Duan Y, Wang SH, Song J, Mironova Y, Ming GL, Kolodkin AL, Giger RJ.

Elife. 2014 Oct 14;3. doi: 10.7554/eLife.04390.PMID: 25313870 

Loss of Fig4 in both Schwann cells and motor neurons contributes to CMT4J neuropathy.

Vaccari I, Carbone A, Previtali SC, Mironova YA, Alberizzi V, Noseda R, Rivellini C, Bianchi F, Del Carro U, D’Antonio M, Lenk GM, Wrabetz L, Giger RJ, Meisler MH, Bolino A.

Hum Mol Genet. 2015 Jan 15;24(2):383-96. doi: 10.1093/hmg/ddu451. Epub 2014 Sep 3.PMID: 25187576 

Post-transcriptional regulation of GABAB receptor and GIRK1 channels by Nogo receptor 1.

Murthy R, Kim J, Sun X, Giger RJ, Fink DJ, Mata M.

Mol Brain. 2013 Jul 6;6:30. doi: 10.1186/1756-6606-6-30.PMID: 23829864 

Where no synapses go: gatekeepers of circuit remodeling and synaptic strength.

Mironova YA, Giger RJ.

Trends Neurosci. 2013 Jun;36(6):363-73. doi: 10.1016/j.tins.2013.04.003. Epub 2013 May 2. Review.PMID: 23642707 

LDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin.

Stiles TL, Dickendesher TL, Gaultier A, Fernandez-Castaneda A, Mantuano E, Giger RJ, Gonias SL.

J Cell Sci. 2013 Jan 1;126(Pt 1):209-20. doi: 10.1242/jcs.113191. Epub 2012 Nov 6.PMID: 23132925 

Neuronal expression of Fig4 is both necessary and sufficient to prevent spongiform neurodegeneration.

Ferguson CJ, Lenk GM, Jones JM, Grant AE, Winters JJ, Dowling JJ, Giger RJ, Meisler MH.

Hum Mol Genet. 2012 Aug 15;21(16):3525-34. doi: 10.1093/hmg/dds179. Epub 2012 May 11.PMID: 22581779 

NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans.

Dickendesher TL, Baldwin KT, Mironova YA, Koriyama Y, Raiker SJ, Askew KL, Wood A, Geoffroy CG, Zheng B, Liepmann CD, Katagiri Y, Benowitz LI, Geller HM, Giger RJ.

Nat Neurosci. 2012 Mar 11;15(5):703-12. doi: 10.1038/nn.3070.PMID: 22406547 

The nogo receptor family restricts synapse number in the developing hippocampus.

Wills ZP, Mandel-Brehm C, Mardinly AR, McCord AE, Giger RJ, Greenberg ME.

Neuron. 2012 Feb 9;73(3):466-81. doi: 10.1016/j.neuron.2011.11.029.PMID: 22325200 

Congenital CNS hypomyelination in the Fig4 null mouse is rescued by neuronal expression of the PI(3,5)P(2) phosphatase Fig4.

Winters JJ, Ferguson CJ, Lenk GM, Giger-Mateeva VI, Shrager P, Meisler MH, Giger RJ.

J Neurosci. 2011 Nov 30;31(48):17736-51. doi: 10.1523/JNEUROSCI.1482-11.2011.PMID: 22131434 

Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function.

Matsuoka RL, Chivatakarn O, Badea TC, Samuels IS, Cahill H, Katayama K, Kumar SR, Suto F, Chédotal A, Peachey NS, Nathans J, Yoshida Y, Giger RJ, Kolodkin AL.

Neuron. 2011 Aug 11;71(3):460-73. doi: 10.1016/j.neuron.2011.06.009.PMID: 21835343 

VEGF shows its attractive side at the midline.

Dickendesher TL, Giger RJ.

Neuron. 2011 Jun 9;70(5):808-12. doi: 10.1016/j.neuron.2011.05.020.PMID: 21658576 

Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J.

Lenk GM, Ferguson CJ, Chow CY, Jin N, Jones JM, Grant AE, Zolov SN, Winters JJ, Giger RJ, Dowling JJ, Weisman LS, Meisler MH.

PLoS Genet. 2011 Jun;7(6):e1002104. doi: 10.1371/journal.pgen.1002104. Epub 2011 Jun 2.PMID: 21655088 

Crystal structure of the Nogo-receptor-2.

Semavina M, Saha N, Kolev MV, Goldgur Y, Giger RJ, Himanen JP, Nikolov DB.

Protein Sci. 2011 Apr;20(4):684-9. doi: 10.1002/pro.597.PMID: 21308849 

Decorin, erythroblastic leukaemia viral oncogene homologue B4 and signal transducer and activator of transcription 3 regulation of semaphorin 3A in central nervous system scar tissue.

Minor KH, Bournat JC, Toscano N, Giger RJ, Davies SJ.

Brain. 2011 Apr;134(Pt 4):1140-55. doi: 10.1093/brain/awq304. Epub 2010 Nov 28.PMID: 21115466 

An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke.

Li S, Overman JJ, Katsman D, Kozlov SV, Donnelly CJ, Twiss JL, Giger RJ, Coppola G, Geschwind DH, Carmichael ST.

Nat Neurosci. 2010 Dec;13(12):1496-504. doi: 10.1038/nn.2674. Epub 2010 Nov 7.PMID: 21057507 

Oligodendrocyte-myelin glycoprotein and Nogo negatively regulate activity-dependent synaptic plasticity.

Raiker SJ, Lee H, Baldwin KT, Duan Y, Shrager P, Giger RJ.

J Neurosci. 2010 Sep 15;30(37):12432-45. doi: 10.1523/JNEUROSCI.0895-10.2010.PMID: 20844138 

Guidance molecules in axon regeneration.

Giger RJ, Hollis ER 2nd, Tuszynski MH.

Cold Spring Harb Perspect Biol. 2010 Jul;2(7):a001867. doi: 10.1101/cshperspect.a001867. Epub 2010 Jun 2. Review.PMID: 20519341 

A new role for RPTPsigma in spinal cord injury: signaling chondroitin sulfate proteoglycan inhibition.

Duan Y, Giger RJ.

Sci Signal. 2010 Feb 23;3(110):pe6. doi: 10.1126/scisignal.3110pe6.PMID: 20179269

A large-scale chemical screen for regulators of the arginase 1 promoter identifies the soy isoflavone daidzeinas a clinically approved small molecule that can promote neuronal protection or regeneration via a cAMP-independent pathway.

Ma TC, Campana A, Lange PS, Lee HH, Banerjee K, Bryson JB, Mahishi L, Alam S, Giger RJ, Barnes S, Morris SM Jr, Willis DE, Twiss JL, Filbin MT, Ratan RR.

J Neurosci. 2010 Jan 13;30(2):739-48. doi: 10.1523/JNEUROSCI.5266-09.2010.PMID: 20071539 

Semaphorin function in neural plasticity and disease.

Pasterkamp RJ, Giger RJ.

Curr Opin Neurobiol. 2009 Jun;19(3):263-74. doi: 10.1016/j.conb.2009.06.001. Epub 2009 Jun 21. Review.PMID: 19541473 

Molecular basis of the interactions of the Nogo-66 receptor and its homolog NgR2 with myelin-associated glycoprotein: development of NgROMNI-Fc, a novel antagonist of CNS myelin inhibition.

Robak LA, Venkatesh K, Lee H, Raiker SJ, Duan Y, Lee-Osbourne J, Hofer T, Mage RG, Rader C, Giger RJ.

J Neurosci. 2009 May 6;29(18):5768-83. doi: 10.1523/JNEUROSCI.4935-08.2009.PMID: 19420245 

Mechanisms of CNS myelin inhibition: evidence for distinct and neuronal cell type specific receptor systems.

Giger RJ, Venkatesh K, Chivatakarn O, Raiker SJ, Robak L, Hofer T, Lee H, Rader C.

Restor Neurol Neurosci. 2008;26(2-3):97-115. Review.PMID: 18820405

Synaptic function for the Nogo-66 receptor NgR1: regulation of dendritic spine morphology and activity-dependent synaptic strength.

Lee H, Raiker SJ, Venkatesh K, Geary R, Robak LA, Zhang Y, Yeh HH, Shrager P, Giger RJ.

J Neurosci. 2008 Mar 12;28(11):2753-65. doi: 10.1523/JNEUROSCI.5586-07.2008.PMID: 18337405 

The Nogo-66 receptor NgR1 is required only for the acute growth cone-collapsing but not the chronic growth-inhibitory actions of myelin inhibitors.

Chivatakarn O, Kaneko S, He Z, Tessier-Lavigne M, Giger RJ.

J Neurosci. 2007 Jul 4;27(27):7117-24.PMID: 17611264 

Molecular dissection of the myelin-associated glycoprotein receptor complex reveals cell type-specific mechanisms for neurite outgrowth inhibition.

Venkatesh K, Chivatakarn O, Sheu SS, Giger RJ.

J Cell Biol. 2007 May 7;177(3):393-9. Epub 2007 Apr 30.PMID: 17470639 Free

Chimeric rabbit/human Fab and IgG specific for members of the Nogo-66 receptor family selected for species cross-reactivity with an improved phage display vector.

Hofer T, Tangkeangsirisin W, Kennedy MG, Mage RG, Raiker SJ, Venkatesh K, Lee H, Giger RJ, Rader C.

J Immunol Methods. 2007 Jan 10;318(1-2):75-87. Epub 2006 Nov 7.PMID: 17140598 

Probing microtubule +TIPs: regulation of axon branching.

Kornack DR, Giger RJ.

Curr Opin Neurobiol. 2005 Feb;15(1):58-66. Review.PMID: 15721745

The Nogo-66 receptor homolog NgR2 is a sialic acid-dependent receptor selective for myelin-associated glycoprotein.

Venkatesh K, Chivatakarn O, Lee H, Joshi PS, Kantor DB, Newman BA, Mage R, Rader C, Giger RJ.

J Neurosci. 2005 Jan 26;25(4):808-22.PMID: 15673660 

Semaphorin 5A is a bifunctional axon guidance cue regulated by heparan and chondroitin sulfate proteoglycans.

Kantor DB, Chivatakarn O, Peer KL, Oster SF, Inatani M, Hansen MJ, Flanagan JG, Yamaguchi Y, Sretavan DW, Giger RJ, Kolodkin AL.

Neuron. 2004 Dec 16;44(6):961-75.PMID: 15603739 

Transient downregulation of Sema3A mRNA in a rat model for temporal lobe epilepsy. A novel molecular event potentially contributing to mossy fiber sprouting.

Holtmaat AJ, Gorter JA, De Wit J, Tolner EA, Spijker S, Giger RJ, Lopes da Silva FH, Verhaagen J.

Exp Neurol. 2003 Jul;182(1):142-50.PMID: 12821384

Neuropilin-2 mediates axonal fasciculation, zonal segregation, but not axonal convergence, of primary accessory olfactory neurons.

Cloutier JF, Giger RJ, Koentges G, Dulac C, Kolodkin AL, Ginty DD.

Neuron. 2002 Mar 14;33(6):877-92.PMID: 11906695 

Silencing the siren: guidance cue hierarchies at the CNS midline.

Giger RJ, Kolodkin AL.

Cell. 2001 Apr 6;105(1):1-4. Review. No abstract available.PMID: 11300996 

Ectopic adenoviral vector-directed expression of Sema3A in organotypic spinal cord explants inhibits growth of primary sensory afferents.

Pasterkamp RJ, Giger RJ, Baker RE, Hermens WT, Verhaagen J.

Dev Biol. 2000 Apr 15;220(2):129-41.PMID: 10753505 

Frazzled precision guides axons.

Giger RJ, Kolodkin AL.

Nature. 2000 Aug 24;406(6798):841, 843. No abstract available.PMID: 10972274

Comparison of neurotrophin and repellent sensitivities of early embryonic geniculate and trigeminal axons.

Rochlin MW, O’Connor R, Giger RJ, Verhaagen J, Farbman AI.

J Comp Neurol. 2000 Jul 10;422(4):579-93.PMID: 10861527

Neuropilin-2 is required in vivo for selective axon guidance responses to secreted semaphorins.

Giger RJ, Cloutier JF, Sahay A, Prinjha RK, Levengood DV, Moore SE, Pickering S, Simmons D, Rastan S, Walsh FS, Kolodkin AL, Ginty DD, Geppert M.

Neuron. 2000 Jan;25(1):29-41.PMID: 10707970 

Expression of the gene encoding the chemorepellent semaphorin III is induced in the fibroblast component of neural scar tissue formed following injuries of adult but not neonatal CNS.

Pasterkamp RJ, Giger RJ, Ruitenberg MJ, Holtmaat AJ, De Wit J, De Winter F, Verhaagen J.

Mol Cell Neurosci. 1999 Feb;13(2):143-66.PMID: 10192772

Role for semaphorin III and its receptor neuropilin-1 in neuronal regeneration and scar formation?

Pasterkamp RJ, De Winter F, Giger RJ, Verhaagen J.

Prog Brain Res. 1998;117:151-70. Review. No abstract available.PMID: 9932407

Semaphorin III: role in neuronal development and structural plasticity.

Giger RJ, Pasterkamp RJ, Holtmaat AJ, Verhaagen J.

Prog Brain Res. 1998;117:133-49. Review. No abstract available.PMID: 9932406

Neuropilin-2 is a receptor for semaphorin IV: insight into the structural basis of receptor function and specificity.

Giger RJ, Urquhart ER, Gillespie SK, Levengood DV, Ginty DD, Kolodkin AL.

Neuron. 1998 Nov;21(5):1079-92.PMID: 9856463 

Patterning of cortical efferent projections by semaphorin-neuropilin interactions.

Polleux F, Giger RJ, Ginty DD, Kolodkin AL, Ghosh A.

Science. 1998 Dec 4;282(5395):1904-6.PMID: 9836643 

Regulation of semaphorin III/collapsin-1 gene expression during peripheral nerve regeneration.

Pasterkamp RJ, Giger RJ, Verhaagen J.

Exp Neurol. 1998 Oct;153(2):313-27.PMID: 9784290

Adenoviral vector-mediated gene delivery to injured rat peripheral nerve.

Dijkhuizen PA, Pasterkamp RJ, Hermens WT, de Winter F, Giger RJ, Verhaagen J.

J Neurotrauma. 1998 Jun;15(6):387-97.PMID: 9624624

Expression of the axon growth-related neural adhesion molecule TAG-1/axonin-1 in the adult mouse brain.

Wolfer DP, Giger RJ, Stagliar M, Sonderegger P, Lipp HP.

Anat Embryol (Berl). 1998 Mar;197(3):177-85.PMID: 9543336

Anatomical distribution of the chemorepellent semaphorin III/collapsin-1 in the adult rat and human brain: predominant expression in structures of the olfactory-hippocampal pathway and the motor system.

Giger RJ, Pasterkamp RJ, Heijnen S, Holtmaat AJ, Verhaagen J.

J Neurosci Res. 1998 Apr 1;52(1):27-42.PMID: 9556027

Adenoviral vector-mediated expression of B-50/GAP-43 induces alterations in the membrane organization of olfactory axon terminals in vivo.

Holtmaat AJ, Hermens WT, Sonnemans MA, Giger RJ, Van Leeuwen FW, Kaplitt MG, Oestreicher AB, Gispen WH, Verhaagen J.

J Neurosci. 1997 Sep 1;17(17):6575-86.PMID: 9254670 

Neuropilin is a semaphorin III receptor.

Kolodkin AL, Levengood DV, Rowe EG, Tai YT, Giger RJ, Ginty DD.

Cell. 1997 Aug 22;90(4):753-62.PMID: 9288754 

Adenovirus-mediated gene transfer in neurons: construction and characterization of a vector for heterologous expression of the axonal cell adhesion molecule axonin-1.

Giger RJ, Ziegler U, Hermens WT, Kunz B, Kunz S, Sonderegger P.

J Neurosci Methods. 1997 Jan;71(1):99-111.PMID: 9125379

Select item 912537865.

Transient gene transfer to neurons and glia: analysis of adenoviral vector performance in the CNS and PNS.

Hermens WT, Giger RJ, Holtmaat AJ, Dijkhuizen PA, Houweling DA, Verhaagen J.

J Neurosci Methods. 1997 Jan;71(1):85-98.PMID: 9125378

Select item 891583766.

Anatomy of rat semaphorin III/collapsin-1 mRNA expression and relationship to developing nerve tracts during neuroembryogenesis.

Giger RJ, Wolfer DP, De Wit GM, Verhaagen J.

J Comp Neurol. 1996 Nov 18;375(3):378-92.PMID: 8915837

Select item 880536767.

Continuous renewal of the axonal pathway sensor apparatus by insertion of new sensor molecules into the growth cone membrane.

Vogt L, Giger RJ, Ziegler U, Kunz B, Buchstaller A, Hermens WTJMC, Kaplitt MG, Rosenfeld MR, Pfaff DW, Verhaagen J, Sonderegger P.

Curr Biol. 1996 Sep 1;6(9):1153-8.PMID: 8805367 Free Article

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Implications for the domain arrangement of axonin-1 derived from the mapping of its NgCAM binding site.

Rader C, Kunz B, Lierheimer R, Giger RJ, Berger P, Tittmann P, Gross H, Sonderegger P.

EMBO J. 1996 May 1;15(9):2056-68.PMID: 8641271 Free PMC Article

Select item 858641269.

The human TAX1 gene encoding the axon-associated cell adhesion molecule TAG-1/axonin-1: genomic structure and basic promoter.

Kozlov SV, Giger RJ, Hasler T, Korvatska E, Schorderet DF, Sonderegger P.

Genomics. 1995 Nov 20;30(2):141-8.PMID: 8586412

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Binding between the neural cell adhesion molecules axonin-1 and Nr-CAM/Bravo is involved in neuron-glia interaction.

Suter DM, Pollerberg GE, Buchstaller A, Giger RJ, Dreyer WJ, Sonderegger P.

J Cell Biol. 1995 Nov;131(4):1067-81.PMID: 7490283 Free PMC Article

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The gene of chicken axonin-1. Complete structure and analysis of the promoter.

Giger RJ, Vogt L, Zuellig RA, Rader C, Henehan-Beatty A, Wolfer DP, Sonderegger P.

Eur J Biochem. 1995 Feb 1;227(3):617-28.PMID: 7867620 Free Article

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A mutant of human insulin-like growth factor II (IGF II) with the processing sites of proinsulin. Expression and binding studies of processed IGF II.

Zarn JA, Lüthi C, Giger RJ, Sigrist A, Humbel RE.

Eur J Biochem. 1992 Dec 15;210(3):665-9.PMID: 1282887 Free Article